Sep 19

Proposal

Our proposal is to make a tower defence game based on defending bacteria taken on our middle and high school years. The objective is to defeat the bacteria and try not to get hit by one of them cause that will cause the defender to lose control of defending the bacteria and gain upgrades as soon as the bacteria gets killed.

Objective

  • Use Game Sprites and UI
  • Make the game educational and challenge
  • Facts that describes the body immune system

Overview

Before making the game, we’ve decided to make the game based on immune system. The immune system is the body’s defense against infectious organisms and other invaders. Leukocytes are produced or stored in many locations in the body, including the thymus, spleen, and bone marrow. Divided into two: Phagocytes, cells that chew up invading organisms. Lymphocytes, cells that allow the body to remember and recognise previous invaders and help the body destroy them. It has disorders which damages the immune systems based on the game, it reduces the game’s health by one. In the game, we use turrets to fight against the diseases on which one of the turret is good against.

Teams:

  • Alfi (2101693574)
  • Handy (2101693504)
  • Felix (2101693851)

Theory

Has 2 T cells that helps to fight the bacteria: Helper T cell and Cytotoxic T cells. Helper T cell activates humoral and cell-mediated immune responses. Cytotoxic T cells use toxic proteins to kill cells infected by viruses or other intracellular pathogens before pathogens fully mature.

Immune Responses divides into Primary and Secondary immune responses. Memory cells of each type—helper T cell, B cell, and cytotoxic T cell—enable the secondary response.

When antigens are detected, several types of cells work together to recognise them and respond. B-lymphocytes to produce antibodies, which are specialized proteins that lock onto specific antigens. After it produced it prepares to fight for the upcoming diseases.

There are the following disorders as mentioned below:

Autoimmune disorders consists of:

– Rheumatoid arthritis

– Systemic lupus erythematosus (lupus)

– Inflammatory bowel disease (IBD)

– Type 1 diabetes mellitus

– Chronic inflammatory demyelinating polyneuropathy

– Psoriasis

– Graves’ disease

– Hashimoto’s thyroiditis

– Myasthenia gravis

– Vasculitis

Immunodeficiency Disorders consists of:

– DiGeorge syndrome

– Chediak-Higashi syndrome and chronic granulomatous disease

Secondary immunodeficiency Disorders

– HIV (human immunodeficiency virus) infection/AIDS (acquired immunodeficiency syndrome)

Allergic Disorders consists of

– Asthma

– Eczema

– Cancer

Bacteria list

– Mycobacterium

– Pseudomonas

– Haemophilus

– Stapylococcus

– Gut Flora

– Campylobacter

Treatment

– Autoimmune diseases: Only treated by controlling the overactive immune response and bring down inflammation. E.g.: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil) and naproxen (Naprosyn).

– Secondary diseases: The treatment depends on the severity in the deficiency of the immune system.

– Immunodeficiency disorders: Antimicrobial therapy to fight and prevent infections, immune globulin replacement therapy, vaccinations, specialized immune globulins, hematopoietic cell transplant, gene therapy, enzyme replacement therapy, biologics.

– Allergic disorders: Depends on each bacteria.

How they fight against pathogens

– Neutrophils kill bacteria by ingesting them.

– Eosinophlic fights parasites and has a role in allergic reactions.

– Basophil fights in allergic reactions.

– Monocytes ingests bacteria throughout the body. Cells destroy damaged and dead cells.

Game Mechanism

We have our tower defence game, which the goal is to defend the immune system from the invading bacteria. Going into the title screen we can see the start and the about button, start button starts the game and the about button shows the facts about the immune systems. On the menu screen, the HUD screen display the wave, health, the point and the background shows one of the places that the tower can be placed, the path for the invading bacteria and the purple square shows the bacteria coming to invade the body. The turret below shows that it cost one point to place for the later waves.

During the gameplay we first go through the menu, start and about. Start goes to the main game while about goes to the facts of the immune system. The controls for moving the turret is the mouse, and navigation is also used to upgrade and move the turrets. Start at wave 1 the bacteria will go through the turrets and the turrets will automatically shoot. When the wave is cleared, the player can ready up anytime whether he/she wants to upgrade the turret or not. After that, it loops from before and vice versa. Game over when all the lifes are gone.

Conclusion

We know how to make games using construct 2 by using those sprites by making our own via MediBangPaintPro. Also, we know how to handle the events by controlling the sprites and other backgrounds and buttons.

Source

https://www.healthline.com/health/autoimmune-disorders#treatment https://www.historyofvaccines.org/content/articles/human-immune-system-and-infectious-disease https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentID=123&ContentTypeID=134 http://www.superfoodsam.com/super-gut/ https://www.betterhealth.vic.gov.au/health/ConditionsAndTreatments/infections-bacterial-and-viral https://www.immunology.org/public-information/bitesized-immunology/pathogens-and-disease/immune-responses-bacteria https://www.businessinsider.com/microbiome-human-bacteria-gut-intestine-mouth-skin-2015-11/?IR=T/#genus-escherichia-4 https://www.google.co.id/search?q=myositis+bacteria&safe=strict&source=lnms&tbm=isch&sa=X&ved=0ahUKEwiqsd_euvjdAhVBO48KHXk_B4QQ_AUIDigB&biw=1018&bih=677#imgrc=fSRGhTF39e3-OM: https://kidshealth.org/en/parents/immune.html https://www.webmd.com/a-to-z-guides/autoimmune-diseases https://www.sciencedaily.com/releases/2010/06/100614171907.htm https://www.sciencedaily.com/releases/2017/11/171116142058.htm http://allerg.qc.ca/Information_allergique/6_2_secondaire_en.html https://primaryimmune.org/allergies-4 https://www.cancer.gov/about-cancer/treatment/types/immunotherapy https://www.sharecare.com/health/blood-basics/how-white-blood-cells-infection Campbell Biology (2016) Lisa A. Urry, Micahel L.Cain, Steven A.Wasserman, Peter V. Minorsky, Jane B. Reece Unit 7 Chapter 43 Construct 2 and MediabangPaintPro

 

Screenshots:

Main menu background

About background that shows the info when it runs

Game background

From screenshot 4-21

The screenshot for 2nd event shows the buttons for the menu

The screenshot for 3rd event shows the about menu

P.S. Unfortunately, i can’t run the game due to localhost problems (don’t know how to solve it because i tried searching for the problem but it  doesn’t work for mac users)

Game over screen

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